Notch1IC Partially Replaces EBNA2 Function in B Cells Immortalized by Epstein-Barr Virus

Immortalization of B cells by Epstein-Barr virus (EBV) depends on the virally encoded EBNA2 protein. Although not related by sequence, the cellular Notch protein and EBNA2 share several biochemical and functional properties, such as interaction with CBF1 and the ability to activate transcription of...

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Autors principals: Gordadze, Alexey V., Peng, RongSheng, Tan, Jie, Liu, GuoZhen, Sutton, Richard, Kempkes, Bettina, Bornkamm, George W., Ling, Paul D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Transformation and Oncogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114305/
https://ncbi.nlm.nih.gov/pubmed/11390591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.5899-5912.2001
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