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Immunoreceptor Tyrosine-Based Activation Motif-Dependent Signaling by Kaposi's Sarcoma-Associated Herpesvirus K1 Protein: Effects on Lytic Viral Replication

The Kaposi's sarcoma-associated herpesvirus (KSHV) K1 gene encodes a polypeptide bearing an immunoreceptor tyrosine-based activation motif (ITAM) that is constitutively active for ITAM-based signal transduction. Although ectopic overexpression of K1 in cultured fibroblasts can lead to growth transfo...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Lagunoff, Michael, Lukac, David M., Ganem, Don
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114304/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390590/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.5891-5898.2001
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