Immunoreceptor Tyrosine-Based Activation Motif-Dependent Signaling by Kaposi's Sarcoma-Associated Herpesvirus K1 Protein: Effects on Lytic Viral Replication

The Kaposi's sarcoma-associated herpesvirus (KSHV) K1 gene encodes a polypeptide bearing an immunoreceptor tyrosine-based activation motif (ITAM) that is constitutively active for ITAM-based signal transduction. Although ectopic overexpression of K1 in cultured fibroblasts can lead to growth tr...

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Detalles Bibliográficos
Main Authors: Lagunoff, Michael, Lukac, David M., Ganem, Don
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC114304/
https://ncbi.nlm.nih.gov/pubmed/11390590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.5891-5898.2001
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