Membrane-Fusing Capacity of the Human Immunodeficiency Virus Envelope Proteins Determines the Efficiency of CD4(+) T-Cell Depletion in Macaques Infected by a Simian-Human Immunodeficiency Virus

The mechanism of the progressive loss of CD4(+) T lymphocytes, which underlies the development of AIDS in human immunodeficiency virus (HIV-1)-infected individuals, is unknown. Animal models, such as the infection of Old World monkeys by simian-human immunodeficiency virus (SHIV) chimerae, can assis...

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Autori principali: Etemad-Moghadam, Bijan, Rhone, Daniela, Steenbeke, Tavis, Sun, Ying, Manola, Judith, Gelman, Rebecca, Fanton, John W., Racz, Paul, Tenner-Racz, Klara, Axthelm, Michael K., Letvin, Norman L., Sodroski, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC114277/
https://ncbi.nlm.nih.gov/pubmed/11356972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.12.5646-5655.2001
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