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H662 is the linchpin of ATP hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB
The ABC transporter HlyB is a central element of the HlyA secretion machinery, a paradigm of Type I secretion. Here, we describe the crystal structure of the HlyB-NBD (nucleotide-binding domain) with H662 replaced by Ala in complex with ATP/Mg(2+). The dimer shows a composite architecture, in which...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142601/ https://ncbi.nlm.nih.gov/pubmed/15889153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600657 |
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