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Transfer of Primer Binding Site-Mutated Simian Immunodeficiency Virus Vectors by Genetically Engineered Artificial and Hybrid tRNA-Like Primers

Simian immunodeficiency viruses (SIV) harbor primer binding sites (PBS) matching tRNA [Formula: see text] or tRNA [Formula: see text]. To study determinants of primer usage in SIV, a SIVmac239-based vector was impaired by mutating the PBS to a sequence (PBS-X2) with no match to any tRNA. By cotransf...

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Udgivet i:J Virol
Principais autores: Hansen, Anette Chemnitz, Grunwald, Thomas, Lund, Anders Henrik, Schmitz, Alexander, Duch, Mogens, Überla, Klaus, Pedersen, Finn Skou
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114249/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11312366/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.10.4922-4928.2001
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