Enhancement of Hepatitis C Virus RNA Replication by Cell Culture-Adaptive Mutations

Studies of the Hepatitis C virus (HCV) replication cycle have been made possible with the development of subgenomic selectable RNAs that replicate autonomously in cultured cells. In these replicons the region encoding the HCV structural proteins was replaced by the neomycin phosphotransferase gene,...

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Pubblicato in:	J Virol
Autori principali:	Krieger, Nicole, Lohmann, Volker, Bartenschlager, Ralf
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Replication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11312331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.10.4614-4624.2001
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