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Enhancement of Hepatitis C Virus RNA Replication by Cell Culture-Adaptive Mutations

Studies of the Hepatitis C virus (HCV) replication cycle have been made possible with the development of subgenomic selectable RNAs that replicate autonomously in cultured cells. In these replicons the region encoding the HCV structural proteins was replaced by the neomycin phosphotransferase gene,...

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Detalhes bibliográficos
Main Authors: Krieger, Nicole, Lohmann, Volker, Bartenschlager, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114214/
https://ncbi.nlm.nih.gov/pubmed/11312331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.10.4614-4624.2001
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