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Human Papillomavirus Type 16 E6-Induced Degradation of E6TP1 Correlates with Its Ability To Immortalize Human Mammary Epithelial Cells

Recent analyses have identified a number of binding partners for E6, including E6AP, ERC55, paxillin, hDlg, p300, interferon regulatory factor 3, hMCM7, Bak, and E6TP1. Notably, association with E6 targets p53, E6TP1, myc, hMCM7, and Bak for degradation. However, the relative importance of the vario...

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Udgivet i:J Virol
Principais autores: Gao, Qingshen, Singh, Latika, Kumar, Ajay, Srinivasan, Seetha, Wazer, David E., Band, Vimla
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Transformation and Oncogenesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114197/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287601/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.9.4459-4466.2001
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