The LD78β Isoform of MIP-1α Is the Most Potent CC-Chemokine in Inhibiting CCR5-Dependent Human Immunodeficiency Virus Type 1 Replication in Human Macrophages

The CC-chemokines RANTES, macrophage inflammatory protein 1α (MIP-1α), and MIP-1β are natural ligands for the CC-chemokine receptor CCR5. MIP-1α, also known as LD78α, has an isoform, LD78β, which was identified as the product of a nonallelic gene. The two isoforms differ in only 3 amino acids. LD78β...

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Hlavní autoři: Aquaro, Stefano, Menten, Patricia, Struyf, Sofie, Proost, Paul, Van Damme, Jo, De Clercq, Erik, Schols, Dominique
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC114186/
https://ncbi.nlm.nih.gov/pubmed/11287590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.9.4402-4406.2001
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