Papillomavirus Type 16 Oncogenes Downregulate Expression of Interferon-Responsive Genes and Upregulate Proliferation-Associated and NF-κB-Responsive Genes in Cervical Keratinocytes

Infection with high-risk human papillomaviruses (HPV) is a major risk factor for development of cervical cancer. Expression of the HPV E6 and E7 oncoproteins increases in differentiating keratinocytes, resulting in inactivation of the p53 and retinoblastoma proteins, two important transcriptional re...

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Detalhes bibliográficos
Main Authors: Nees, Matthias, Geoghegan, Joel M., Hyman, Tehila, Frank, Stephan, Miller, Lance, Woodworth, Craig D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114174/
https://ncbi.nlm.nih.gov/pubmed/11287578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.9.4283-4296.2001
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