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Adeno-Associated Virus Type 2-Mediated Gene Transfer: Altered Endocytic Processing Enhances Transduction Efficiency in Murine Fibroblasts

Adeno-associated virus type 2 (AAV) is a single-stranded-DNA-containing, nonpathogenic human parvovirus that is currently in use as a vector for human gene therapy. However, the transduction efficiency of AAV vectors in different cell and tissue types varies widely. In addition to the lack of expres...

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Udgivet i:J Virol
Principais autores: Hansen, Jonathan, Qing, Keyun, Srivastava, Arun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114153/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.9.4080-4090.2001
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