Oncolytic Activity of Vesicular Stomatitis Virus Is Effective against Tumors Exhibiting Aberrant p53, Ras, or Myc Function and Involves the Induction of Apoptosis

We have recently shown that vesicular stomatitis virus (VSV) exhibits potent oncolytic activity both in vitro and in vivo (S. Balachandran and G. N. Barber, IUBMB Life 50:135–138, 2000). In this study, we further demonstrated, in vivo, the efficacy of VSV antitumor action by showing that tumors that...

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Главные авторы: Balachandran, Siddharth, Porosnicu, Mercedes, Barber, Glen N.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Gene Therapy
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC114141/
https://ncbi.nlm.nih.gov/pubmed/11238874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.7.3474-3479.2001
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