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Naturally Occurring Deletional Mutation in the C-Terminal Cytoplasmic Tail of CCR5 Affects Surface Trafficking of CCR5

CCR5 is an essential coreceptor for the cellular entry of R5 strains of human immunodeficiency virus type 1 (HIV-1). CCR5-893(−) is a single-nucleotide deletion mutation which is observed exclusively in Asians (M. A. Ansari-Lari, et al., Nat. Genet. 16:221–222, 1997). This mutant gene produces a CCR...

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Udgivet i:J Virol
Principais autores: Shioda, Tatsuo, Nakayama, Emi E., Tanaka, Yuetsu, Xin, Xiaomi, Liu, Huanliang, Kawana-Tachikawa, Ai, Kato, Atsushi, Sakai, Yuko, Nagai, Yoshiyuki, Iwamoto, Aikichi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114139/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238872/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.7.3462-3468.2001
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