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Haemophilia A: carrier detection and prenatal diagnosis by linkage analysis using DNA polymorphism.

Restriction fragment length polymorphisms (RFLPs) within or close to the factor VIII locus are very useful for genetic linkage analysis. Such RFLPs allow a mutant allele to be tracked in a family, segregating haemophilia A even when, as is usually the case, the precise mutation causing failure to sy...

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Bibliografske podrobnosti
Main Authors: Tuddenham, E G, Goldman, E, McGraw, A, Kernoff, P B
Format: Artigo
Jezik:Inglês
Izdano: 1987
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1141166/
https://ncbi.nlm.nih.gov/pubmed/2889753
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