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Iron chelation studies using desferrioxamine and the potential oral chelator, 1,2-dimethyl-3-hydroxypyrid-4-one, in normal and iron loaded rats.

A novel iron chelator, 1,2-dimethyl-3-hydroxypyrid-4-one, and desferrioxamine were compared for their ability to remove iron and for their site of action in iron release in rats. Repeated intraperitoneal injections of the chelators in rats with widespread tissue labelling by 59Fe derived from transf...

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Detalhes bibliográficos
Main Authors: Kontoghiorghes, G J, Sheppard, L, Hoffbrand, A V, Charalambous, J, Tikerpae, J, Pippard, M J
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140972/
https://ncbi.nlm.nih.gov/pubmed/3584483
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