Mitochondrial Carrier Homolog 2 Is a Target of tBID in Cells Signaled To Die by Tumor Necrosis Factor Alpha

BID, a proapoptotic BCL-2 family member, plays an essential role in the tumor necrosis factor alpha (TNF-α)/Fas death receptor pathway in vivo. Activation of the TNF-R1 receptor results in the cleavage of BID into truncated BID (tBID), which translocates to the mitochondria and induces the activatio...

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Main Authors: Grinberg, Michal, Schwarz, Michal, Zaltsman, Yehudit, Eini, Tzipi, Niv, Hagit, Pietrokovski, Shmuel, Gross, Atan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140633/
https://ncbi.nlm.nih.gov/pubmed/15899861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4579-4590.2005
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