Rab3D Regulates a Novel Vesicular Trafficking Pathway That Is Required for Osteoclastic Bone Resorption

Rab3 proteins are a subfamily of GTPases, known to mediate membrane transport in eukaryotic cells and play a role in exocytosis. Our data indicate that Rab3D is the major Rab3 species expressed in osteoclasts. To investigate the role of Rab3D in osteoclast physiology we examined the skeletal archite...

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Autores principales: Pavlos, Nathan J., Xu, Jiake, Riedel, Dietmar, Yeoh, Joyce S. G., Teitelbaum, Steven L., Papadimitriou, John M., Jahn, Reinhard, Ross, F. Patrick, Zheng, Ming H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140603/
https://ncbi.nlm.nih.gov/pubmed/15923639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.12.5253-5269.2005
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