Oct-3/4 Maintains the Proliferative Embryonic Stem Cell State via Specific Binding to a Variant Octamer Sequence in the Regulatory Region of the UTF1 Locus

The POU transcription factor Oct-3/4 has been shown to be critical for maintaining embryonic stem (ES) cell character. However, the molecular mechanisms underlying its function remain elusive. We have previously shown that among the POU transcription factor family of proteins, Oct-3/4 alone is able...

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Detalhes bibliográficos
Main Authors: Nishimoto, Masazumi, Miyagi, Satoru, Yamagishi, Toshiyuki, Sakaguchi, Takehisa, Niwa, Hitoshi, Muramatsu, Masami, Okuda, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140574/
https://ncbi.nlm.nih.gov/pubmed/15923625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.12.5084-5094.2005
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