Reovirus ςNS Protein Is Required for Nucleation of Viral Assembly Complexes and Formation of Viral Inclusions

Progeny virions of mammalian reoviruses are assembled in the cytoplasm of infected cells at discrete sites termed viral inclusions. Studies of temperature-sensitive (ts) mutant viruses indicate that nonstructural protein ςNS and core protein μ2 are required for synthesis of double-stranded (ds) RNA,...

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Detalhes bibliográficos
Main Authors: Becker, Michelle M., Goral, Mehmet I., Hazelton, Paul R., Baer, Geoffrey S., Rodgers, Steven E., Brown, Earl G., Coombs, Kevin M., Dermody, Terence S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114052/
https://ncbi.nlm.nih.gov/pubmed/11152519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1459-1475.2001
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