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Quantitating intracellular transport of polyplexes by spatio-temporal image correlation spectroscopy

Quantitatively understanding how nonviral gene delivery vectors (polyplexes) are transported inside cells is essential before they can be optimized for gene therapy and medical applications. In this study, we used spatio-temporal image correlation spectroscopy (ICS) to follow polymer-nucleic acid pa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kulkarni, Rajan P., Wu, David D., Davis, Mark E., Fraser, Scott E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140437/
https://ncbi.nlm.nih.gov/pubmed/15897455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501950102
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