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Mannosyl-Diinositolphospho-Ceramide, the Major Yeast Plasma Membrane Sphingolipid, Governs Toxicity of Kluyveromyces lactis Zymocin

Kluyveromyces lactis zymocin, a trimeric (αβγ) protein toxin complex, inhibits proliferation of Saccharomyces cerevisiae cells. Here we present an analysis of kti6 mutants, which resist exogenous zymocin but are sensitive to intracellular expression of its inhibitory γ-toxin subunit, suggesting that...

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Detalhes bibliográficos
Main Authors: Zink, Sabrina, Mehlgarten, Constance, Kitamoto, Hiroko K., Nagase, Junko, Jablonowski, Daniel, Dickson, Robert C., Stark, Michael J. R., Schaffrath, Raffael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140091/
https://ncbi.nlm.nih.gov/pubmed/15879522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.4.5.879-889.2005
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