Immunogenicity and Protective Efficacy of Oligomeric Human Immunodeficiency Virus Type 1 gp140

The biologically active form of the human immunodeficiency virus type 1 (HIV-1) envelope (Env) glycoprotein is oligomeric. We previously described a soluble HIV-1 IIIB Env protein, gp140, with a stable oligomeric structure composed of uncleaved gp120 linked to the ectodomain of gp41 (P. L. Earl, C....

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Détails bibliographiques
Auteurs principaux: Earl, Patricia L., Sugiura, Wataru, Montefiori, David C., Broder, Christopher C., Lee, Susan A., Wild, Carl, Lifson, Jeffrey, Moss, Bernard
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2001
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC113961/
https://ncbi.nlm.nih.gov/pubmed/11134278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.2.645-653.2001
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