Potent, Broad-Spectrum Inhibition of Human Immunodeficiency Virus Type 1 by the CCR5 Monoclonal Antibody PRO 140

CCR5 serves as a requisite fusion coreceptor for clinically relevant strains of human immunodeficiency virus type 1 (HIV-1) and provides a promising target for antiviral therapy. However, no study to date has examined whether monoclonal antibodies, small molecules, or other nonchemokine agents posse...

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Bibliographische Detailangaben
Hauptverfasser: Trkola, Alexandra, Ketas, Thomas J., Nagashima, Kirsten A., Zhao, Lu, Cilliers, Tonie, Morris, Lynn, Moore, John P., Maddon, Paul J., Olson, William C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC113953/
https://ncbi.nlm.nih.gov/pubmed/11134270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.2.579-588.2001
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