Potent, Broad-Spectrum Inhibition of Human Immunodeficiency Virus Type 1 by the CCR5 Monoclonal Antibody PRO 140

CCR5 serves as a requisite fusion coreceptor for clinically relevant strains of human immunodeficiency virus type 1 (HIV-1) and provides a promising target for antiviral therapy. However, no study to date has examined whether monoclonal antibodies, small molecules, or other nonchemokine agents posse...

Full description

Saved in:
Bibliographic Details
Main Authors: Trkola, Alexandra, Ketas, Thomas J., Nagashima, Kirsten A., Zhao, Lu, Cilliers, Tonie, Morris, Lynn, Moore, John P., Maddon, Paul J., Olson, William C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC113953/
https://ncbi.nlm.nih.gov/pubmed/11134270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.2.579-588.2001
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items