A Recombinant Newcastle Disease Virus with Low-Level V Protein Expression Is Immunogenic and Lacks Pathogenicity for Chicken Embryos

Newcastle disease virus (NDV) edits its P-gene mRNA by inserting a nontemplated G residue(s) at a conserved editing site (3′-UUUUUCCC-template strand). In the wild-type virus, three amino-coterminal P-gene-derived proteins, P, V, and W, are produced at frequencies of approximately 68, 29, and 2%, re...

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Autores principales: Mebatsion, Teshome, Verstegen, Stefan, De Vaan, Leonarda T. C., Römer-Oberdörfer, Angela, Schrier, Carla C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC113934/
https://ncbi.nlm.nih.gov/pubmed/11119610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.1.420-428.2001
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