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Multiple biological responses are induced by glycosylation-deficient hepatocyte growth factor

HGF (hepatocyte growth factor), a heterodimeric glycoprotein composed of α- and β-chains, exerts biological activities through the c-Met receptor tyrosine kinase. The α-chain has three glycosylation sites, while the β-chain has two; however, the role of sugar chains on HGF is still unknown. To addre...

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Autori principali: Fukuta, Kazuhiro, Matsumoto, Kunio, Nakamura, Toshikazu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138963/
https://ncbi.nlm.nih.gov/pubmed/15693751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041698
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