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Roles of Rac and p38 kinase in the activation of cytosolic phospholipase A(2) in response to PMA

The roles of Rac and p38 kinase in the activation of cPLA(2) (cytosolic PLA(2)) in Rat-2 fibroblasts were investigated. In the present study, we found that PMA activates cPLA(2) by a Rac-p38 kinase-dependent pathway. Consistent with this, Rac, if activated, was shown to stimulate cPLA(2) in a p38 ki...

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Detalhes bibliográficos
Main Authors: You, Hye Jin, Woo, Chang-Hoon, Choi, Eun-Young, Cho, Sung-Hoon, Yoo, Yung Joon, Kim, Jae-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138960/
https://ncbi.nlm.nih.gov/pubmed/15689183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041614
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