Biosynthesis of heparin. Relationship between the polymerization and sulphation processes.

Incubation of a mouse mastocytoma microsomal fraction with UDP-[3H]GlcA and UDP-GlcNAc yielded proteoglycans containing non-sulphated polysaccharide chains. Similar incubations performed in the presence of sulphate donor 3'-phosphoadenosine 5'-phosphosulphate (PAPS) produced both sulphated...

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Bibliographic Details
Main Authors: Lidholt, K, Kjellén, L, Lindahl, U
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138928/
https://ncbi.nlm.nih.gov/pubmed/2572219
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