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The novel thermogenic beta-adrenergic agonist Ro 16-8714 increases the interscapular brown-fat beta-receptor-adenylate cyclase and the uncoupling-protein mRNA level in obese (fa/fa) Zucker rats.

In obese (fa/fa) rats both the total (-)-isoprenaline- and NaF-stimulated adenylate cyclase activities of interscapular brown-adipose-tissue (IBAT) plasma membranes were decreased as compared with lean rats by 40 and 38% respectively. An acute treatment with Ro 16-8714 increased (-)-isoprenaline- an...

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Detaylı Bibliyografya
Asıl Yazarlar: Muzzin, P, Revelli, J P, Ricquier, D, Meier, M K, Assimacopoulos-Jeannet, F, Giacobino, J P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138890/
https://ncbi.nlm.nih.gov/pubmed/2572217
Etiketler: Etiketle
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