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Identification of a cysteine residue at the active site of Escherichia coli isocitrate lyase.

Escherichia coli isocitrate lyase was inactivated by iodacetate in a pseudo-first-order process. Complete inactivation was associated with the incorporation of only one carboxymethyl group per enzyme subunit. The substrate and products of the enzyme protected against inactivation, suggesting that th...

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Detalles Bibliográficos
Main Authors: Nimmo, H G, Douglas, F, Kleanthous, C, Campbell, D G, MacKintosh, C
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138844/
https://ncbi.nlm.nih.gov/pubmed/2673221
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