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NMR structure of a DNA duplex containing nucleoside analog 1-(2′-deoxy-β-d-ribofuranosyl)-3-nitropyrrole and the structure of the unmodified control

The three-dimensional structures of two DNA duplexes d(CATGAGTAC)·d(GTACXCATG) (1) and d(CATGAGTAC)·d(GTACTCATG) (2), where X represents 1-(2′-deoxy-β-d-ribofuranosyl)-3-nitropyrrole, were solved using high resolution nuclear magnetic resonance spectroscopy and restrained molecular dynamics. Good co...

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Detalhes bibliográficos
Main Authors: Klewer, Douglas A., Hoskins, Aaron, Zhang, Peiming, Davisson, V. J., Bergstrom, Donald E., LiWang, Andy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113877/
https://ncbi.nlm.nih.gov/pubmed/11071940
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