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Bombesin stimulation of inositol 1,4,5-trisphosphate generation and intracellular calcium release is amplified in a cell line overexpressing the N-ras proto-oncogene.

Bombesin stimulation of T15 cells in which the inducible N-ras oncogene is overexpressed caused elevated production of inositol phosphates compared to uninduced cells [Wakelam, Davies, Houslay, McKay, Marshall & Hall (1986) Nature (London) 323, 173-176]. This elevated response is shown here to r...

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Detalhes bibliográficos
Main Authors: Lloyd, A C, Davies, S A, Crossley, I, Whitaker, M, Houslay, M D, Hall, A, Marshall, C J, Wakelam, M J
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138749/
https://ncbi.nlm.nih.gov/pubmed/2669738
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