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The Box C/D motif directs snoRNA 5′-cap hypermethylation

The 5′-cap structure of most spliceosomal small nuclear RNAs (snRNAs) and certain small nucleolar RNAs (snoRNAs) undergoes hypermethylation from a 7-methylguanosine to a 2,2,7-trimethylguanosine structure. 5′-Cap hypermethylation of snRNAs is dependent upon a conserved sequence element known as the...

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Autori principali: Speckmann, Wayne A., Terns, Rebecca M., Terns, Michael P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC113864/
https://ncbi.nlm.nih.gov/pubmed/11071934
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