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On the mechanism of the reduction by thyroid hormone of beta-adrenergic relaxation rate stimulation in rat heart.

The effects of beta-adrenergic stimulation on the relaxation rate and the Ca2+-transport rate in sarcoplasmic reticulum of hypothyroid, euthyroid and hyperthyroid rat hearts were studied. Administration of isoproterenol (0.1 microM) to perfused, electrically stimulated hearts (5 Hz) caused a decreas...

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Bibliographic Details
Main Authors: Beekman, R E, van Hardeveld, C, Simonides, W S
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138495/
https://ncbi.nlm.nih.gov/pubmed/2541682
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