Feedback control of ornithine decarboxylase expression by polyamines. Analysis of ornithine decarboxylase mRNA distribution in polysome profiles and of translation of this mRNA in vitro.

Cell growth and differentiation require the presence of optimal concentrations of polyamines. Ornithine decarboxylase (ODC) catalyses the first and rate-controlling step in polyamine synthesis. In studies using cultures of Ehrlich ascites-tumour cells, we have shown that the expression of ODC is sub...

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Main Authors: Holm, I, Persson, L, Stjernborg, L, Thorsson, L, Heby, O
格式: Artigo
語言:Inglês
出版: 1989
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138367/
https://ncbi.nlm.nih.gov/pubmed/2495790
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