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Phosphorylation of mismatch repair proteins MSH2 and MSH6 affecting MutSα mismatch-binding activity

Mismatch repair (MMR) is involved in the removal of mispaired bases from DNA and thus plays an important role in the maintenance of genomic stability and the prevention of mutations and cancer. Moreover, MMR triggers genotoxicity and apoptosis upon processing of DNA lesions such as O(6)-methylguanin...

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Udgivet i:Nucleic Acids Res
Principais autores: Christmann, Markus, Tomicic, Maja T., Kaina, Bernd
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113836/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11972333/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.9.1959
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