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Clavulanate inactivation of Staphylococcus aureus beta-lactamase.

The interaction of clavulanic acid with beta-lactamase from Staphylococcus aureus was investigated, particularly with a view to determining whether conformational effects are involved. The inactivation at neutral pH is essentially stoichiometric, leading to an inactive species with an enamine chromo...

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Detalhes bibliográficos
Main Authors: Rizwi, I, Tan, A K, Fink, A L, Virden, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138342/
https://ncbi.nlm.nih.gov/pubmed/2494991
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