Hepatic ketogenesis in newborn pigs is limited by low mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase activity.

In newborn-pig hepatocytes, the rate of oleate oxidation is extremely low, despite a very low malonyl-CoA concentration. By contrast, the sensitivity of carnitine palmitoyltransferase (CPT) I to malonyl-CoA inhibition is high, as suggested by the very low concentration of malonyl-CoA required for 50...

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Main Authors: Duée, P H, Pégorier, J P, Quant, P A, Herbin, C, Kohl, C, Girard, J
格式: Artigo
語言:Inglês
出版: 1994
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138002/
https://ncbi.nlm.nih.gov/pubmed/7907471
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