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Structure and contribution to the heparin cofactor II-mediated inhibition of thrombin of naturally oversulphated sequences of dermatan sulphate.

Dermatan sulphate (DS) obtained from bovine and pig mucosa and pig skin, and charge-enriched fractions of a selected DS preparation, were characterized in terms of charge density, M(r) and disaccharide composition of chondroitin ABC lyase digests, and by 13C-n.m.r. spectroscopy. Besides the major Id...

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Detalhes bibliográficos
Main Authors: Mascellani, G, Liverani, L, Bianchini, P, Parma, B, Torri, G, Bisio, A, Guerrini, M, Casu, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137745/
https://ncbi.nlm.nih.gov/pubmed/8280062
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