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Studies of the active site of m-calpain and the interaction with calpastatin.

Calpain autolyses in the presence of Ca2+. In the case of m-calpain (80 + 30 kDa) the first product is an 80 + 18 kDa species which has an intact large subunit and the C-terminal Ca(2+)-binding domain of the small subunit. It was possible to bind E64 into the active site of calpain in the presence o...

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Detalles Bibliográficos
Main Authors: Crawford, C, Brown, N R, Willis, A C
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137665/
https://ncbi.nlm.nih.gov/pubmed/8250833
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