Lipoxin synthase activity of human platelet 12-lipoxygenase.

Human platelets and megacaryocytes generate lipoxins from exogenous leukotriene A4 (LTA4). We examined the role of human 12-lipoxygenase (12-LO) in lipoxin generation with recombinant histidine-tagged human platelet enzyme (6His-12-LO), partially purified 12-LO from human platelets (HPL 12-LO) and,...

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Bibliographic Details
Main Authors: Romano, M, Chen, X S, Takahashi, Y, Yamamoto, S, Funk, C D, Serhan, C N
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137664/
https://ncbi.nlm.nih.gov/pubmed/8250832
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