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Mechanism-based inactivation of gastric peroxidase by mercaptomethylimidazole.

The mechanism of inhibition of gastric peroxidase (GPO) activity by mercaptomethylimidazole (MMI), an inducer of gastric acid secretion, has been investigated. Incubation of purified GPO with MMI in the presence of H2O2 results in irreversible inactivation of the enzyme. No significant inactivation...

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Bibliographic Details
Main Authors: Bandyopadhyay, U, Bhattacharyya, D K, Banerjee, R K
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137657/
https://ncbi.nlm.nih.gov/pubmed/8250859
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