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Mechanism-based inactivation of gastric peroxidase by mercaptomethylimidazole.

The mechanism of inhibition of gastric peroxidase (GPO) activity by mercaptomethylimidazole (MMI), an inducer of gastric acid secretion, has been investigated. Incubation of purified GPO with MMI in the presence of H2O2 results in irreversible inactivation of the enzyme. No significant inactivation...

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Autors principals: Bandyopadhyay, U, Bhattacharyya, D K, Banerjee, R K
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137657/
https://ncbi.nlm.nih.gov/pubmed/8250859
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