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Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum.

Bisphosphonates are a class of synthetic pyrophosphate analogues. Some are known to be potent inhibitors of osteoclast-mediated bone resorption in vivo, but their mechanisms of action are unclear. The order of potency of bisphosphonates as inhibitors of bone resorption closely matches the order of p...

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Detalhes bibliográficos
Main Authors: Rogers, M J, Ji, X, Russell, R G, Blackburn, G M, Williamson, M P, Bayless, A V, Ebetino, F H, Watts, D J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137591/
https://ncbi.nlm.nih.gov/pubmed/7945256
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