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The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells.

Glycogen synthase kinase 3 (GSK3) was inhibited by 50% within 5 min when A431 cells were stimulated with epidermal growth factor (EGF). The inhibition was unaffected by rapamycin at concentrations which blocked the activation of p70 S6 kinase, and reversed by incubation with protein phosphatase-1. E...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Saito, Y, Vandenheede, J R, Cohen, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137551/
https://ncbi.nlm.nih.gov/pubmed/7945252
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