Mastoparan may activate GTP hydrolysis by Gi-proteins in HL-60 membranes indirectly through interaction with nucleoside diphosphate kinase.

The wasp venom, mastoparan (MP), activates reconstituted pertussis toxin (PTX)-sensitive G-proteins in a receptor-independent manner. We studied the effects of MP and its analogue, mastoparan 7 (MP 7), on G-protein activation in HL-60 cells and a reconstituted system and on nucleoside diphosphate ki...

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Bibliographische Detailangaben
Hauptverfasser: Klinker, J F, Hagelüken, A, Grünbaum, L, Heilmann, I, Nürnberg, B, Harhammer, R, Offermanns, S, Schwaner, I, Ervens, J, Wenzel-Seifert, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137504/
https://ncbi.nlm.nih.gov/pubmed/7998971
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