Proteoglycans isolated from dissociative extracts of differently aged human articular cartilage: characterization of naturally occurring hyaluronan-binding fragments of aggrecan.

Proteoglycans extracted with 4 M guanidinium chloride from young (mean 20 years) or old (mean 79 years) macroscopically normal human articular cartilage were separated by density gradient centrifugation and Q-Sepharose chromatography and characterized by gradient gel SDS/PAGE and immunodetection bef...

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Detalles Bibliográficos
Main Authors: Vilim, V, Fosang, A J
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137416/
https://ncbi.nlm.nih.gov/pubmed/7818495
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