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Structure of the human cyclo-oxygenase-2 gene.

Cyclo-oxygenase (Cox), a rate-limiting enzyme in the synthesis of prostanoids, is encoded by two genes, Cox-1 and Cox-2, which are differentially expressed and regulated. Human Cox-1 and -2 polypeptides share 61% primary sequence identity. While the expression of Cox-1 is maximal in quiescent cells....

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Autors principals: Appleby, S B, Ristimäki, A, Neilson, K, Narko, K, Hla, T
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137291/
https://ncbi.nlm.nih.gov/pubmed/7945196
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