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Shear-stress-induced von Willebrand factor binding to platelets causes the activation of tyrosine kinase(s).

Pathological arterial blood flow generates fluid shear stresses that directly cause platelet aggregation. The mechanism of shear-induced platelet aggregation is incompletely understood, but involves von Willebrand factor (vWF) binding to platelet glycoprotein (GP) Ib and GP IIb-IIIa, leading to the...

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Bibliografische gegevens
Hoofdauteurs: Razdan, K, Hellums, J D, Kroll, M H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1994
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137285/
https://ncbi.nlm.nih.gov/pubmed/7524475
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