Interactions of plant acetohydroxy acid isomeroreductase with reaction intermediate analogues: correlation of the slow, competitive, inhibition kinetics of enzyme activity and herbicidal effects.

N-Hydroxy-N-isopropyloxamate (IpOHA) is known to inhibit extremely tightly (Ki of 22 pM) the bacterial acetohydroxy acid isomeroreductase (EC 1.1.1.86) [Aulabaugh and Schloss (1990) Biochemistry 29, 2824-2830], the second enzyme of the branched-chain-amino-acid-biosynthetic pathway. Yet, although th...

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Détails bibliographiques
Auteurs principaux: Dumas, R, Cornillon-Bertrand, C, Guigue-Talet, P, Genix, P, Douce, R, Job, D
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137060/
https://ncbi.nlm.nih.gov/pubmed/8053906
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