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Linkage disequilibrium maps and association mapping

The causal chain between a gene and its effect on disease susceptibility cannot be understood until the effect has been localized in the DNA sequence. Recently, polymorphisms incorporated in the HapMap Project have made linkage disequilibrium (LD) the most powerful tool for localization. The genetic...

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Podrobná bibliografie
Hlavní autor: Morton, Newton E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137007/
https://ncbi.nlm.nih.gov/pubmed/15931377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25032
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