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Linkage disequilibrium maps and association mapping
The causal chain between a gene and its effect on disease susceptibility cannot be understood until the effect has been localized in the DNA sequence. Recently, polymorphisms incorporated in the HapMap Project have made linkage disequilibrium (LD) the most powerful tool for localization. The genetic...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1137007/ https://ncbi.nlm.nih.gov/pubmed/15931377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25032 |
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