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Linkage disequilibrium maps and association mapping

The causal chain between a gene and its effect on disease susceptibility cannot be understood until the effect has been localized in the DNA sequence. Recently, polymorphisms incorporated in the HapMap Project have made linkage disequilibrium (LD) the most powerful tool for localization. The genetic...

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Detalles Bibliográficos
Autor Principal: Morton, Newton E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2005
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137007/
https://ncbi.nlm.nih.gov/pubmed/15931377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25032
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