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Inhibition of myeloperoxidase by benzoic acid hydrazides.

Myeloperoxidase is the most abundant protein in neutrophils and catalyses the conversion of H2O2 and chloride into HOCl. To help clarify the role of this enzyme in bacterial killing and inflammation, a specific and potent inhibitor needs to be identified. We have studied a series of benzoic acid hyd...

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Autors principals: Kettle, A J, Gedye, C A, Hampton, M B, Winterbourn, C C
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136962/
https://ncbi.nlm.nih.gov/pubmed/7772042
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