N-glycosylation of human interferon-gamma: glycans at Asn-25 are critical for protease resistance.

Human interferon-gamma (IFN-gamma) is a secretory, dimeric glycoprotein that forms a compact globular structure with potential N-linked glycosylation sites at Asn-25 and Asn-97 on the surface of the dimer. In natural leucocyte IFN-gamma (nIFN-gamma), 52%, 39% and 9% of the monomers are core-glycosyl...

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Detalles Bibliográficos
Main Authors: Sareneva, T, Pirhonen, J, Cantell, K, Julkunen, I
Formato: Artigo
Idioma:Inglês
Publicado: 1995
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136836/
https://ncbi.nlm.nih.gov/pubmed/7755594
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